Gelucire 5013 Melting Point
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Gelucire 5013 melting point. GMS has an HLB value in the. However with a higher melting point and longer fatty acid chains it can have a release retarding effect when used at high. Gelucire® 50/13 (stearoyl polyoxyl-32 glycerides) is a nonionic water-dispersible surfactant for lipid-based formulations to solubilize and increase oral bioavailability of poorly water-soluble APIs.
These are available with range of properties depending on their HLB and melting point range of 33 to 65 °C. Alternatively, the powders may be compressed into tablets. Melting point 54.5–58.5 o C.
Gelucire® 50/13 is a well characterized excipient, supported by numerous publications and worldwide precedence of use including FDA IID listing. People make our name. Gelucire is derived from mixtures of mono, di and triglycerides with PEG esters of fatty acids.
Generally, self-emulsifying formulations provide a rapid (immediate. You can also browse global suppliers,vendor,prices,Price,manufacturers of Gelucire 50-13(-05-8). Are solids (higher melting points) and so are suitable also for preparation of granules and powders which can subsequently be filled into hard shell capsules or sachets.
Gelucire 50/13 is an excipient composed of fatty acid (C16 and C18) esters of glycerol, PEG esters and free PEG. Curcumin was dissolved in Gelucire 50/13 stearoyl polyethylene glycol (32) glycerides and was stabilized with either Gelucire 50/13 or Pluronic F127. At last,Gelucire 50-13(-05-8) safety, risk, hazard.
Self-emulsifies in aqueous media forming a fine dispersion, i.e., microemulsion (SMEDDS). It melts at approximately 50°C and has hydrophilic-lipophilic balance (HLB) value of 13 6, 7. It has similar surfactive properties to Gelucire® 44/14.
The particle size was around 295 ± nm and zeta potential was around −16 mV. They have a wide variety of applications in oral and topical formulation. Visit ChemicalBook To find more Gelucire 50-13(-05-8) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes.
Due to its low melting point and waxy behavior, Gelucire®44/14 acts as a binder, thereby strongly increasing the disintegration time of tablets produced via compression.
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